Mouse Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3) Protein
234€ (10 µg)
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935106861
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name
Mouse Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067780
tested applications
WB, SDS-PAGE
Description
Mouse Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3) is a recombinant Mouse protein fromproduced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Leukocyte Immunoglobulin Like Receptor Subfamily B, Member 3 (LILRB3) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 27.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser410-Ser631 Tag: N-terminal His tag |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P97484 |
| Alias | Leukocyte immunoglobulin-like receptor subfamily B member 3,Leukocyte immunoglobulin-like receptor 3,HL9,ILT5,LIR3,PIRB,CD85A,ILT-5,LIR-3,PIR-B,LILRA6,CD85 antigen-like family member A,Immunoglobulin-like transcript 5,Monocyte inhibitory receptor HL9 |
| Background | Protein LILRB3 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
LILRB3 (Leukocyte Immunoglobulin-Like Receptor B3) is a member of the leukocyte immunoglobulin-like receptor (LILR) family, a group of receptors involved in regulating the immune response. LILRB3, also known as CD85A or ILT5 (Immunoglobulin-like Transcript 5), is predominantly expressed on myeloid cells, including monocytes, macrophages, neutrophils, and dendritic cells. These receptors play a crucial role in immune regulation by mediating inhibitory signals that prevent excessive activation of the immune system, contributing to the maintenance of immune homeostasis. LILRB3 belongs to the inhibitory subfamily of LILR receptors, which means it primarily dampens immune responses. It achieves this through the recruitment of tyrosine phosphatases, which inhibit activating signaling pathways, thereby reducing inflammatory responses and promoting immune tolerance. This regulation is important for preventing autoimmune reactions and minimizing tissue damage during inflammatory processes.
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