Mouse Leucine-Rich Repeat Neuronal Protein 1 (LINGO1) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits LINGO1
proveedor
Abbexareference
abx531004Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 ELISA Kit is an ELISA kit against Mouse Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 (Lingo1).
Background
LINGO1 is a transmembrane protein predominantly expressed in the central nervous system (CNS) and is involved in the regulation of neuronal and oligodendrocyte function. Structurally, it contains leucine-rich repeats (LRRs) and immunoglobulin (Ig) domains that facilitate protein-protein interactions. LINGO1 plays a critical role in inhibiting axonal regeneration and myelination by interacting with receptors like Nogo receptor 1 (NgR1) in neuronal signaling pathways. Its overexpression has been implicated in neurodegenerative diseases such as multiple sclerosis (MS) and Parkinson’s disease, where impaired remyelination and axonal repair contribute to disease progression. LINGO1 has emerged as a therapeutic target in CNS disorders, with LINGO1 antagonists showing promise in preclinical studies for promoting remyelination and neural repair. Genetic polymorphisms in LINGO1 have also been associated with susceptibility to essential tremor, highlighting its significance in movement disorders.
Características del producto
category
ELISA Kits
immunogen target
Leucine-Rich Repeat Neuronal Protein 1 (LINGO1)
reactivity
Mouse
test range
0.312 ng/ml - 20 ng/ml
sensitivity
< 0.11 ng/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
LERN1,MRT64,LRRN6A,UNQ201,Leucine-rich repeat neuronal protein 6A,Leucine-rich repeat neuronal protein 1,Leucine-rich repeat and immunoglobulin domain-containing protein 1,Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
LINGO1
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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