Mouse Leucine-rich repeat-containing protein 68 (LRRC68) ELISA Kit
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Descripción del producto
Mouse Leucine-rich repeat-containing protein 68 (LRRC68) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leucine-rich repeat-containing protein 68 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Especificaciones del producto
| Alias | LRRC68, KIAA1986, LRRC68,Protein phosphatase 1 regulatory subunit 37 |
| Assay Data | Quantitative |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Background | Elisa kits for PPP1R37 |
| Category | ELISA Kits |
| Detection Method | Colorimetric |
| Dry Ice | No |
| Form | Lyophilized |
| Gene ID | 232947 |
| Immunogen Target | Leucine-rich repeat-containing protein 68 (LRRC68) |
| Name | Mouse Leucine-rich repeat-containing protein 68 (LRRC68) ELISA Kit |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Price | 715 |
| Provider | Abbexa |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx531463 |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Size 1 | 96 tests |
| Status | RUO |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Tested Applications | ELISA |
| UniProt ID | Q8BKR5 |
Descripcion del producto en español
Background en español
PPP1R37 is a regulatory subunit that modulates the activity and specificity of protein phosphatase 1 (PP1), a key enzyme involved in dephosphorylation of serine/threonine residues on target proteins. PPP1R37 regulates pathways controlling cellular processes such as cell adhesion, migration, and cytoskeletal organization by targeting PP1 to substrates like focal adhesion proteins and cytoskeletal regulators. It plays a role in maintaining cellular homeostasis and responding to mechanical or stress signals through its modulation of phosphatase activity. PPP1R37 is expressed in various tissues, including muscle and connective tissues, where it participates in extracellular matrix remodeling and cellular mechanotransduction. Dysregulation of PPP1R37 is linked to pathological conditions such as fibrosis, cancer, and impaired tissue repair due to abnormal phosphatase activity and disrupted cellular signaling. Knockdown studies reveal defects in cell adhesion, reduced migration, and impaired stress response, highlighting its role in regulating PP1 activity during cellular signaling and tissue maintenance.
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