Mouse Leucine-rich repeat-containing protein 4 (LRRC4) ELISA Kit
715€ (96 tests)
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Leucine-rich repeat-containing protein 4 (LRRC4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531568
tested applications
ELISA
Descripción del producto
Mouse Leucine-rich repeat-containing protein 4 (LRRC4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leucine-rich repeat-containing protein 4 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Especificaciones del producto
| Alias | Netrin-G2 ligand (NGL-2) |
| Assay Data | Quantitative |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Background | Elisa kits for LRRC4 |
| Category | ELISA Kits |
| Detection Method | Colorimetric |
| Dry Ice | No |
| Form | Lyophilized |
| Gene ID | 192198 |
| Immunogen Target | Leucine-rich repeat-containing protein 4 (LRRC4) |
| Name | Mouse Leucine-rich repeat-containing protein 4 (LRRC4) ELISA Kit |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
| Price | 715 |
| Provider | Abbexa |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Reference | abx531568 |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Size 1 | 96 tests |
| Status | RUO |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Tested Applications | ELISA |
| UniProt ID | Q99PH1 |
Descripcion del producto en español
Background en español
LRRC4, also known as netrin-G ligand 2 (NGL-2), is a leucine-rich repeat-containing protein involved in synaptic organization, neuronal development, and cell signaling. It serves as a postsynaptic adhesion molecule that interacts with netrin-G2, facilitating synapse formation, maintenance, and stability in the central nervous system. LRRC4 is highly expressed in the brain, particularly in regions associated with synaptic plasticity, learning, and memory. It regulates axon guidance, dendritic development, and excitatory synaptic transmission by interacting with cytoskeletal proteins and signaling molecules. Dysregulation or mutations in LRRC4 are associated with neurological disorders, including autism spectrum disorders (ASD) and intellectual disabilities, where impaired synaptic organization disrupts neuronal connectivity. LRRC4 also exhibits tumor-suppressive properties in gliomas by inhibiting cell proliferation, migration, and survival pathways. Knockout studies reveal impaired synaptic function, altered dendritic morphology, and reduced neuronal connectivity, highlighting its essential role in neural circuit development, synaptic organization, and brain function.
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