Mouse Leucine-rich repeat-containing protein 19 (LRRC19) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Leucine-rich repeat-containing protein 19 (LRRC19) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx531355
tested applications
ELISA
Description
Mouse Leucine-rich repeat-containing protein 19 (LRRC19) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Leucine-rich repeat-containing protein 19 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Leucine-rich repeat-containing protein 19 (LRRC19) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8BZT5 |
| Gene ID | 100061 |
| Alias | LRRC19 |
| Background | Elisa kits for LRRC19 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRRC19 is a membrane protein implicated in innate immune signaling where it functions as a pattern recognition receptor (PRR) involved in the detection of microbial components it directly activates downstream pathways such as nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) cascades essential for initiating inflammatory responses LRRC19 is predominantly expressed in dendritic cells and macrophages where it contributes to pathogen recognition and the activation of adaptive immunity by promoting antigen presentation studies suggest LRRC19 plays a critical role in the regulation of pro-inflammatory cytokine production and may act as a mediator in host-pathogen interactions its dysregulation has been associated with chronic inflammatory diseases and autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease ongoing research is exploring its potential as a target for modulating inflammatory responses and its involvement in maintaining immune homeostasis during infections and sterile inflammation
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