Leucine-Rich Repeat-Containing Protein 19 (LRRC19) Antibody

Product specifications

Primary Antibodies

Leucine-Rich Repeat-Containing Protein 19 (LRRC19)

Rabbit

Human

WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.

Polyclonal

Unconjugated

IgG

Purified through a protein A column, followed by peptide affinity purification.

80 µl

400 µl

Liquid

ELISA, WB

PBS containing 0.09% sodium azide.

Shipped within 5-10 working days.

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

No

Q9H756

LRRC19

Antibody anti-LRRC19

RUO

Descripción

LRRC19 is a membrane protein implicated in innate immune signaling where it functions as a pattern recognition receptor (PRR) involved in the detection of microbial components it directly activates downstream pathways such as nuclear factor-kappa B (NF-κB) and mitogen-activated protein kinase (MAPK) cascades essential for initiating inflammatory responses LRRC19 is predominantly expressed in dendritic cells and macrophages where it contributes to pathogen recognition and the activation of adaptive immunity by promoting antigen presentation studies suggest LRRC19 plays a critical role in the regulation of pro-inflammatory cytokine production and may act as a mediator in host-pathogen interactions its dysregulation has been associated with chronic inflammatory diseases and autoimmune conditions such as rheumatoid arthritis and inflammatory bowel disease ongoing research is exploring its potential as a target for modulating inflammatory responses and its involvement in maintaining immune homeostasis during infections and sterile inflammation

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