Mouse Leucine Rich Repeat Containing Protein 15 (LRRC15) CLIA Kit
871€ (96 tests)
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935106861
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name
Mouse Leucine Rich Repeat Containing Protein 15 (LRRC15) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx496662
tested applications
CLIA
Description
Mouse Leucine Rich Repeat Containing Protein 15 (LRRC15) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) Kit against Leucine Rich Repeat Containing Protein 15 (LRRC15).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Leucine Rich Repeat Containing Protein 15 (LRRC15) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.128 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q80X72 |
| Gene ID | 74488 |
| Alias | LIBLeucine-rich repeat protein induced by beta-amyloid homolog ,hLib |
| Background | CLIA Kits LRRC15 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
LRRC15 is a collagen-binding protein with a significant role in regulating extracellular matrix (ECM) remodeling and cell-matrix interactions it is widely expressed in stromal cells and tumor-associated fibroblasts where it participates in modulating cell adhesion and migration particularly in cancer and wound healing contexts LRRC15 has been identified as a critical component of the tumor microenvironment facilitating tumor progression and metastasis by influencing ECM organization and stiffness it is also involved in immune modulation through its interactions with immune cell receptors recent studies indicate its expression is upregulated in fibrotic diseases such as idiopathic pulmonary fibrosis (IPF) and systemic sclerosis implicating it in pathological ECM deposition and remodeling LRRC15's potential as a therapeutic target is being explored particularly in oncology where its expression correlates with resistance to immune checkpoint inhibitors and poor prognosis in several cancers ongoing research aims to clarify its regulatory mechanisms in ECM biology and its cross-talk with other signaling pathways driving tissue repair and fibrosis
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