Mouse L-Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse L-Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx388569
tested applications
ELISA
Description
Mouse Aminoadipate Semialdehyde Dehydrogenase Phosphopantetheinyl Transferase (AASDHPPT) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Aminoadipate Semialdehyde Dehydrogenase Phosphopantetheinyl Transferase (AASDHPPT) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | L-Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase (AASDHPPT) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | < 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9CQF6 |
| Gene ID | 67618 |
| Alias | AASD-PPT,ACPS,CGI-80,LYS2,LYS5 |
| Background | Elisa Kits for: AASDHPPT |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Descripción
L-Aminoadipate-Semialdehyde Dehydrogenase-Phosphopantetheinyl Transferase (AASDHPPT) is a bifunctional enzyme involved in lysine degradation and coenzyme A biosynthesis. It catalyzes the oxidation of L-aminoadipate semialdehyde to L-aminoadipate and facilitates the attachment of a 4'-phosphopantetheinyl group to carrier proteins, a key step in activating proteins involved in fatty acid and polyketide synthesis. AASDHPPT is expressed ubiquitously but is particularly active in mitochondria, where lysine degradation contributes to cellular energy metabolism and detoxification. Dysregulation of AASDHPPT is associated with metabolic conditions linked to impaired amino acid catabolism, such as glutaric aciduria type 1. Its dual function also highlights its importance in fatty acid metabolism, and mutations affecting AASDHPPT activity may lead to energy imbalances and oxidative stress. Therapeutic approaches targeting AASDHPPT are being explored for metabolic disorders and mitochondrial dysfunction.
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