Mouse Killer cell lectin-like receptor subfamily B member 1A (KLRB1A) ELISA Kit

Este producto es parte de KLRB1 - killer cell lectin like receptor B1
Mouse Killer cell lectin-like receptor subfamily B member 1A (KLRB1A) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for KLRB1

proveedor

Abbexa

reference

abx530250

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Killer cell lectin-like receptor subfamily B member 1A (KLRB1A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Killer cell lectin-like receptor subfamily B member 1A concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

Killer cell lectin-like receptor B1 (KLRB1), also known as CD161, is a type II transmembrane protein predominantly expressed on subsets of immune cells, especially natural killer (NK) cells and T cells. KLRB1 plays a key role in modulating immune responses and is especially involved in the regulation of cytotoxicity and cytokine production, particularly among NK and T cell subsets. KLRB1 belongs to the C-type lectin superfamily and is encoded by the KLRB1 gene located on chromosome 12p13 in humans. KLRB1’s expression is associated with an inhibitory effect on immune cell activation, helping maintain immune homeostasis, prevent excessive immune responses, and aid in the modulation of immune activity against infections, tumors, and in inflammatory diseases. KLRB1 is primarily known for its role as a receptor for the carbohydrate-bearing protein LLT1 (lectin-like transcript 1, or CLEC2D). This interaction facilitates cell-cell communication and can mediate inhibitory signaling in NK cells and some T cell subsets, potentially leading to immune tolerance in certain tissues and tumors.

Características del producto

category

ELISA Kits


immunogen target

Killer cell lectin-like receptor subfamily B member 1A (KLRB1A)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

Killer cell lectin-like receptor subfamily B member 1,NKR,CD161,CLEC5B,NKR-P1,NKRP1A,NKR-P1A,hNKR-P1A,C-type lectin domain family 5 member B,Natural killer cell surface protein P1A


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

KLRB1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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