Mouse Interleukin 20 (IL20) Protein

Este producto es parte de IL20 - interleukin 20
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208€ (10 µg)

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935106861
info@markelab.com
name
Mouse Interleukin 20 (IL20) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx654007
tested applications
WB, SDS-PAGE

Description

Mouse Interleukin 20 (IL20) Protein is a Recombinant Mouse protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interleukin 20 (IL20)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 21.3 kDa  Observed MW: 21 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Leu25-Leu176
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 90%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
IL-20,IL10D,ZCYTO10,Cytokine Zcyto10
Background
Protein IL20
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interleukin 20 (IL20) is a member of the IL-10 cytokine family, which includes structurally related cytokines like IL-19, IL-22, IL-24, and IL-26. These cytokines share common biological functions in regulating immune responses, inflammation, and tissue homeostasis. IL-20, in particular, is predominantly associated with the modulation of skin, lung, and other epithelial tissues, where it exerts its effects on inflammation, tissue repair, and the innate immune response. IL-20 is produced by various cell types, including monocytes, keratinocytes, endothelial cells, and fibroblasts. Its expression is induced by pro-inflammatory cytokines such as IL-1β, IL-6, and TNF-α, particularly in tissues experiencing inflammation or injury. IL-20 acts primarily on epithelial and immune cells to regulate tissue homeostasis and inflammation, making it an important mediator in diseases like psoriasis, rheumatoid arthritis, and pulmonary inflammation.

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