Mouse Interleukin 17 Receptor A (IL17RA) Protein
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935106861
info@markelab.com
Precio
247€ (10 µg)
Protein IL17RA
proveedor
Abbexareference
abx067465Tested Applications
WB, SDS-PAGEreactivity
status
RUOclonality
Descripción
Recombinant Interleukin 17 Receptor A (IL17RA) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Background
Interleukin-17 receptor A (IL17RA) is a protein critical for immune responses, especially in mediating host defense against extracellular pathogens and in inflammatory processes. IL17RA is the primary receptor for the IL-17 family of cytokines, a group known to play key roles in driving immune responses by recruiting neutrophils and promoting inflammation. Among the IL-17 family, IL-17A and IL-17F are particularly significant in immune signaling via IL17RA. IL-17 cytokines and their receptors have been extensively studied for their involvement in autoimmune diseases, inflammatory conditions, and some cancers, where dysregulated IL-17 signaling leads to excessive or persistent inflammation. IL17RA, as a receptor, is broadly expressed across various cell types, including epithelial cells, fibroblasts, macrophages, and dendritic cells. This widespread expression pattern reflects the receptor’s role in both the immune and non-immune cells, enabling it to participate in the body's initial responses to infection and inflammation.
Características del producto
category
Proteins and Peptides
origin
Mouse
host
E. coli
immunogen target
Interleukin 17 Receptor A (IL17RA)
host
E. coli
conjugation
Unconjugated
form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
tested applications
WB, SDS-PAGE
size 1
10 µg
size 2
50 µg
size 3
100 µg
size 4
200 µg
size 5
500 µg
observerd MW
Molecular Weight: Calculated MW: 30.3 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg590-Trp848 Tag: N-terminal His tag
expression
Recombinant
purity
> 95%
buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
or code
IL17RA
dry ice
No
availability
Shipped within 5-12 working days.
alias
IL-17 receptor A,CD217,IL17R,IMD51,CANDF5,CDw217,IL-17RA
uniprot id
note
This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.
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