Human Interleukin 17 Receptor A (IL17RA) Protein

Este producto es parte de IL17RA -interleukin 17 receptor A
Human Interleukin 17 Receptor A (IL17RA) Protein

Pida mas información

935106861

info@markelab.com

Precio

442€ (50 µg)

Protein IL17RA

proveedor

Abbexa

reference

abx651378

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Interleukin 17 Receptor A (IL17RA) Protein (Active) is an active protein from Human.


Background

Interleukin-17 receptor A (IL17RA) is a protein critical for immune responses, especially in mediating host defense against extracellular pathogens and in inflammatory processes. IL17RA is the primary receptor for the IL-17 family of cytokines, a group known to play key roles in driving immune responses by recruiting neutrophils and promoting inflammation. Among the IL-17 family, IL-17A and IL-17F are particularly significant in immune signaling via IL17RA. IL-17 cytokines and their receptors have been extensively studied for their involvement in autoimmune diseases, inflammatory conditions, and some cancers, where dysregulated IL-17 signaling leads to excessive or persistent inflammation. IL17RA, as a receptor, is broadly expressed across various cell types, including epithelial cells, fibroblasts, macrophages, and dendritic cells. This widespread expression pattern reflects the receptor’s role in both the immune and non-immune cells, enabling it to participate in the body's initial responses to infection and inflammation.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Interleukin 17 Receptor A (IL17RA)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

50 µg


size 2

100 µg


size 3

200 µg


size 4

500 µg


size 5

1 mg


observerd MW

Molecular Weight: Calculated MW: 19.0 kDa Observed MW: 18 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Pro377-Phe534 Tag: N-terminal His tag


purity

> 90%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL17RA


dry ice

No


availability

Shipped within 5-7 working days.


alias

IL-17 receptor A,CD217,IL17R,IMD51,CANDF5,CDw217,IL-17RA


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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