Mouse Interleukin 13 Receptor Alpha 2 (IL13Ra2) Protein

Este producto es parte de IL13RA2 - interleukin 13 receptor subunit alpha 2
Mouse Interleukin 13 Receptor Alpha 2 (IL13Ra2) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein IL13RA2

proveedor

Abbexa

reference

abx067445

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Recombinant Interleukin 13 Receptor Alpha 2 (IL13Ra2) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

Interleukin-13 receptor subunit alpha-2 (IL13RA2) is a protein encoded by the IL13RA2 gene, which functions as part of the immune system’s response to inflammation and certain immune-regulatory mechanisms. IL13RA2 is closely related to interleukin-13 receptor subunit alpha-1 (IL13RA1), both of which bind to the cytokine interleukin-13 (IL-13). However, IL13RA2 is distinctive in that it acts as a “decoy” receptor, binding IL-13 with high affinity but not actively initiating intracellular signaling, thereby modulating the effects of IL-13 on immune responses. IL13RA2 has roles in regulating allergic reactions and fibrotic processes and is often upregulated in various pathological conditions, including certain cancers. The protein's interactions with IL-13 have implications for tissue remodeling, fibrosis, and immune regulation, making it an important target in the fields of immunology, oncology, and fibrosis research.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Interleukin 13 Receptor Alpha 2 (IL13Ra2)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 14.2 kDa Observed MW (SDS-PAGE): 11 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asn228-Ile338 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

IL13RA2


dry ice

No


availability

Shipped within 5-7 working days.


alias

IL-13 receptor subunit alpha-2,CT19,IL-13R,IL13BP,CD213A2,Interleukin-13-binding protein


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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