Mouse Interleukin 10 (IL10) Protein

Product specifications

Proteins and Peptides

HEK293 cells

Mouse

Molecular Weight: Calculated MW: 19.47 kDa  Observed MW (SDS-PAGE): 22 kDa
Sequence Fragment: Met1-178Ser
Tag: C-terminal His tag

Recombinant

>95% (SDS-PAGE)

20 µg

100 µg

Lyophilized Reconstitute in sterile H2O. Do not vortex.

SDS-PAGE

Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.

Shipped within 5-15 working days.

Store lyophilized between -20 °C and -80 °C.

No

P18893

16153

CSIF,GVHDS,IL-10,IL10A,TGIF,Cytokine synthesis inhibitory factor

Protein IL10

RUO

This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

IL10 is an anti-inflammatory cytokine produced by macrophages, T regulatory cells, and other immune cells to suppress excessive immune responses and maintain tissue homeostasis IL10 signaling occurs through the IL-10 receptor (IL10R) and activates the JAK/STAT3 pathway, inhibiting the production of pro-inflammatory cytokines such as TNF-α, IL1β, and IL6 It plays a pivotal role in immune tolerance, limiting damage caused by chronic inflammation and infections Dysregulation of IL10 expression is associated with autoimmune diseases, such as Crohn's disease, multiple sclerosis, and psoriasis IL10 also exerts immunosuppressive effects in the tumor microenvironment, facilitating tumor progression and immune evasion due to its inhibitory influence on T cells and antigen-presenting cells IL10-based therapies are being explored for managing inflammatory diseases and promoting immune modulation in cancer and chronic infections

Related Products

Bovine IL-10(Interleukin 10) ELISA Kit

Ver Producto

Canine IL-10(Interleukin 10) ELISA Kit

Ver Producto

Chicken IL-10(Interleukin-10) ELISA Kit

Ver Producto