Mouse Interferon Alpha 2 (IFNA2) Protein

169€ (10 µg)
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935106861
info@markelab.com
name
Mouse Interferon Alpha 2 (IFNA2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693866
tested applications
SDS-PAGE
Description
Mouse Interferon α-2 Protein is a recombinant protein from Mouse produced in E. coli. Recombinant Mouse Interferon alpha-2 is produced by our E.coli expression system and the target gene encoding Cys24-Glu190 is expressed.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Interferon α-2 |
Host | E. coli |
Origin | Mouse |
Observed MW | Molecular Weight: 19.5 kDa Sequence Fragment: Cys24-Glu190 |
Expression | Recombinant |
Purity | > 95% (SDS-PAGE) |
Size 1 | 10 µg |
Size 2 | 50 µg |
Form | Lyophilized |
Tested Applications | SDS-PAGE |
Buffer | 20mM PB, 100mM Nacl, pH7.4. |
Availability | Shipped within 5-15 working days. |
Storage | Store at < -20°C. |
Dry Ice | No |
UniProt ID | P01573 |
Alias | IFNA,leIF A,IFN-alphaA,IFN-alpha-2,Interferon alpha-A,IFNA2A,IFNA2B,IFNA2C |
Background | Protein IFNA2 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Interferon Alpha 2 (IFNA2) is one of the most studied type I interferons due to its significant role in antiviral defense and its clinical applications. Similar to IFNA1, IFNA2 is secreted by immune cells in response to viral infections and engages IFNAR to activate antiviral and immune-modulating pathways. IFNA2 has been extensively utilized in therapeutic settings, including recombinant IFNA2 (e.g., interferon-alpha-2a and -2b) for the treatment of viral hepatitis, certain cancers like melanoma, and hematologic malignancies. It enhances the immune system's ability to combat infections and tumors by promoting immune cell activation, increasing antigen presentation, and inducing apoptosis in infected or malignant cells. However, its use is often associated with side effects like flu-like symptoms and immune dysregulation, necessitating careful administration and monitoring.
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