Mouse Interferon Alpha-2 (IFNA2) Protein
234€ (10 µg)
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935106861
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name
Mouse Interferon Alpha-2 (IFNA2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx693866
tested applications
SDS-PAGE
Description
Interferon Alpha-2 (IFNA2) protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Interferon Alpha-2 (IFNA2) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Cys24-Glu190 |
| Origin | Mouse |
| Observed MW | 19.5 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20 mM PBS, 100 mM Nacl, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | P01573 |
| Alias | IFNA,leIF A,IFN-alphaA,IFN-alpha-2,Interferon alpha-A,IFNA2A,IFNA2B,IFNA2C |
| Background | Protein IFNA2 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Interferon Alpha 2 (IFNA2) is one of the most studied type I interferons due to its significant role in antiviral defense and its clinical applications. Similar to IFNA1, IFNA2 is secreted by immune cells in response to viral infections and engages IFNAR to activate antiviral and immune-modulating pathways. IFNA2 has been extensively utilized in therapeutic settings, including recombinant IFNA2 (e.g., interferon-alpha-2a and -2b) for the treatment of viral hepatitis, certain cancers like melanoma, and hematologic malignancies. It enhances the immune system's ability to combat infections and tumors by promoting immune cell activation, increasing antigen presentation, and inducing apoptosis in infected or malignant cells. However, its use is often associated with side effects like flu-like symptoms and immune dysregulation, necessitating careful administration and monitoring.
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