Human Interferon Alpha 2 (IFNa2) Protein

Este producto es parte de IFNA2 - interferon alpha 2
Product Graph
247€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Human Interferon Alpha 2 (IFNa2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067329
tested applications
WB, SDS-PAGE

Description

Recombinant Interferon alpha 2 is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Interferon Alpha 2 (IFNa2)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 23.0 kDa  Observed MW (SDS-PAGE): 23 kDa

Concentration: Prior to lyophilization: 200 µg/ml

Sequence Fragment: Cys24-Glu188

Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
P01563
Alias
IFNA,leIF A,IFN-alphaA,IFN-alpha-2,Interferon alpha-A,IFNA2A,IFNA2B,IFNA2C
Background
Protein IFNA2
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Interferon Alpha 2 (IFNA2) is one of the most studied type I interferons due to its significant role in antiviral defense and its clinical applications. Similar to IFNA1, IFNA2 is secreted by immune cells in response to viral infections and engages IFNAR to activate antiviral and immune-modulating pathways. IFNA2 has been extensively utilized in therapeutic settings, including recombinant IFNA2 (e.g., interferon-alpha-2a and -2b) for the treatment of viral hepatitis, certain cancers like melanoma, and hematologic malignancies. It enhances the immune system's ability to combat infections and tumors by promoting immune cell activation, increasing antigen presentation, and inducing apoptosis in infected or malignant cells. However, its use is often associated with side effects like flu-like symptoms and immune dysregulation, necessitating careful administration and monitoring.

Related Products

EH4506

Human IFNα2 (Interferon alpha-2) ELISA Kit

Ver Producto
EM0780

Mouse IFN-α2 (Interferon alpha-2) ELISA Kit

Ver Producto
P4418

Recombinant Human IFNA2

Ver Producto