Mouse Intercellular Adhesion Molecule 3 (ICAM3) CLIA Kit
643.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Mouse Intercellular Adhesion Molecule 3 (ICAM3) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx197175
tested applications
CLIA
Description
Mouse intercellular adhesion molecule 3 (ICAM-3) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against intercellular adhesion molecule 3 (ICAM-3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Intercellular Adhesion Molecule 3 (ICAM3) |
| Reactivity | Mouse |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Test Range | 78 pg/ml - 5000 pg/ml |
| Sensitivity | 46.9 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | CD50,CDW50,ICAM-R,Intercellular adhesion molecule 3 |
| Background | CLIA Kits ICAM3 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Intercellular Adhesion Molecule 3 (ICAM3), also known as CD50, is a member of the immunoglobulin superfamily (IgSF) that plays a crucial role in cell-cell adhesion and immune system regulation. It is expressed predominantly on leukocytes, especially resting lymphocytes, and interacts with integrins to mediate various immune responses, including leukocyte trafficking, T-cell activation, and antigen recognition. ICAM3 is particularly involved in the early stages of immune responses, functioning as a ligand for leukocyte function-associated antigen-1 (LFA-1), an integrin found on T cells and other leukocytes. ICAM-3 acts as a facilitator of immunological synapse formation, helping leukocytes adhere to antigen-presenting cells and promoting signaling pathways critical for immune activation. Its interaction with integrins also promotes adhesion between leukocytes and endothelial cells, an important step in the migration of immune cells to sites of inflammation or infection. ICAM-3 is essential in regulating leukocyte dynamics and activation during immune surveillance and host defense.
Related Products
Human ICAM-3(Intercellular adhesion molecule 3) ELISA Kit
Ver Producto
Mouse ICAM-3(intercellular adhesion molecule 3) ELISA Kit
Ver Producto
anti- ICAM3 antibody
ICAM proteins are ligands for the leukocyte adhesion protein LFA-1(integrin alpha-L/beta-2)(PubMed:1448173). ICAM3 is also a ligand for integrin alpha-D/beta-2. In association with integrin alpha-L/beta-2, contributes to apoptotic neutrophil phagocytosis by macrophages(PubMed:23775590).
Ver Producto