Mouse Integrin Alpha X / CD11C (ITGAX) Protein

221€ (10 µg)
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935106861
info@markelab.com
name
Mouse Integrin Alpha X / CD11C (ITGAX) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx167234
tested applications
WB, SDS-PAGE
Description
Integrin Alpha X Protein is a recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | Integrin Alpha X / CD11C (ITGAX) |
Host | E. coli |
Origin | Mouse |
Conjugation | Unconjugated |
Observed MW | Molecular Weight: Calculated MW: 53.9 kDa Observed MW (SDS-PAGE): 54 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Arg907-Val1115 Tag: N-terminal His tag and GST tag |
Expression | Recombinant |
Purity | > 95% |
Size 1 | 10 µg |
Size 2 | 50 µg |
Size 3 | 100 µg |
Size 4 | 200 µg |
Size 5 | 500 µg |
Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
Tested Applications | WB, SDS-PAGE |
Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl and 5% Trehalose. |
Availability | Shipped within 5-7 working days. |
Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Alias | CD11C,SLEB6,CD11 antigen-like family member C,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,Leukocyte adhesion receptor p150,95 |
Background | Protein ITGAX |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Integrin Subunit Alpha X (ITGAX), commonly referred to as CD11c, is a member of the integrin family that dimerizes with ITGB2 to form the CR4 receptor. ITGAX is highly expressed on dendritic cells and is used as a hallmark marker for this cell type. It mediates cell adhesion, migration, and antigen presentation by enabling dendritic cells to interact with the extracellular matrix and other immune cells. ITGAX also participates in phagocytosis and immune responses against pathogens by functioning as a complement receptor. Its role in immune regulation makes it a focus in studies of chronic inflammatory diseases, atherosclerosis, and cancer immunology. The protein's expression is also commonly analyzed in histological studies to evaluate dendritic cell populations in various tissues.
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