Mouse Integrin alpha-E (ITGAE) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ITGAE
proveedor
Abbexareference
abx528820Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Integrin alpha-E (ITGAE) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Integrin alpha-E concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Integrin subunit alpha E, known as ITGAE, is a critical component of the immune system, particularly in regulating immune cell retention in epithelial tissues. ITGAE, often referred to as CD103 in immunological contexts, partners with the integrin beta 7 subunit to form the heterodimeric receptor αEβ7. This integrin is specifically expressed on subsets of immune cells, including mucosal T lymphocytes, dendritic cells, and natural killer (NK) cells, where it binds to E-cadherin, an adhesion molecule on epithelial cells. By binding E-cadherin, αEβ7 plays a critical role in localizing lymphocytes to epithelial tissues, particularly within the gut, skin, and lungs, where immune surveillance is essential. This adhesion mechanism enables αEβ7-expressing cells to provide targeted immune responses and maintain tissue integrity.
Características del producto
category
ELISA Kits
immunogen target
Integrin alpha-E (ITGAE)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CD103,HUMINAE,Integrin alpha-E,HML-1 antigen,Integrin alpha-IEL,Mucosal lymphocyte 1 antigen
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ITGAE
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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