935106861
info@markelab.com
Precio
687.5€ (96 tests)
Mouse Integrin alpha-6 (ITGA6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Integrin alpha-6 concentrations in tissue homogenates, cell lysates and other biological fluids.
Integrin subunit alpha 6 (ITGA6) is part of the integrin family, a group of transmembrane receptors that mediate cell adhesion and interactions with the extracellular matrix (ECM). ITGA6 specifically pairs with either integrin beta 1 (ITGB1) or integrin beta 4 (ITGB4) to form the α6β1 and α6β4 integrins, which primarily bind to laminins, an essential component of the basement membrane. These integrin complexes play critical roles in tissue integrity, cellular architecture, and signal transduction, mediating functions such as cell adhesion, migration, proliferation, and differentiation. In pathological conditions, dysregulation of ITGA6 has been implicated in cancer progression, tissue fibrosis, and inflammatory diseases. Due to its involvement in cancer cell migration and invasion, ITGA6 is considered a potential therapeutic target, particularly in cancers of epithelial origin.
ELISA Kits
Integrin alpha-6 (ITGA6)
Mouse
0.156 ng/ml - 10 ng/ml
Quantitative
Colorimetric
Tissue homogenates,Cell lysates,Other biological fluids
96 tests
JEB6,CD49f,VLA-6,ITGA6A,ITGA6B,Integrin alpha-6,CD49 antigen-like family member F
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
ITGA6
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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