Mouse Importin subunit alpha-3 (KPNA3) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for KPNA3
proveedor
Abbexareference
abx528291Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Importin subunit alpha-3 (KPNA3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Importin subunit alpha-3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
KPNA3, or importin-α3, is another member of the importin-α family that mediates the nuclear import of cargo proteins with classical nuclear localization signals (NLS). It interacts with importin-β to form a complex that transports cargo proteins through the nuclear pore complex (NPC). KPNA3 is expressed in various tissues and is particularly important in regulating nuclear transport during cell signaling, differentiation, and immune responses. It has roles in viral infections, where it mediates the nuclear import of viral proteins such as influenza and HIV components, aiding viral replication. Dysregulation of KPNA3 is associated with neurological disorders and cancer, where it influences nuclear transport of transcription factors and oncogenes. Knockout and functional studies show its essential role in maintaining cellular homeostasis and regulating nuclear import efficiency during development and stress responses.
Características del producto
category
ELISA Kits
immunogen target
Importin subunit alpha-3 (KPNA3)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
QIP2,Importin alpha Q2,Importin subunit alpha-4,SRP1,SRP4,IPOA4,SPG88; Hsrp1,SRP1gamma
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
KPNA3
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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