Mouse IL-6 Receptor Subunit Beta / GP130 (IL6ST) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
562.5€ (96 tests)
Elisa Kits IL6ST
proveedor
Abbexareference
abx254415Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse IL-6 Receptor Subunit Beta / GP130 (IL6ST) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse IL-6 Receptor Subunit Beta / GP130 (IL6ST) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
The interleukin 6 signal transducer (IL6ST), also known as gp130 or CD130, is a transmembrane protein that plays a crucial role in immune system regulation and cellular signaling. It functions as a common signal transducer for the IL-6 family of cytokines, which includes IL-6, IL-11, leukemia inhibitory factor (LIF), ciliary neurotrophic factor (CNTF), cardiotrophin-1 (CT-1), and others. These cytokines are involved in various physiological processes, including immune responses, hematopoiesis, inflammation, and tissue regeneration. IL6ST/gp130 is a key receptor component in the JAK/STAT signaling pathway and is widely expressed in various cell types, including immune cells, neurons, hepatocytes, and endothelial cells. Its broad expression and signaling capability allow it to mediate responses across different tissues, contributing to a range of cellular functions such as proliferation, differentiation, survival, and apoptosis. Dysregulation of gp130 signaling has been associated with multiple conditions, including autoimmune diseases, chronic inflammatory disorders, and various cancers.
Características del producto
category
ELISA Kits
immunogen target
IL-6 Receptor Subunit Beta / GP130 (IL6ST)
reactivity
Mouse
test range
15.6 pg/ml - 1000 pg/ml
sensitivity
9.38 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
Interleukin-6 receptor subunit beta,CD130,GP130,HIES4,IMD94,STWS2,CDW130,HIES4A,HIES4B,IL-6RB,Sgp130,IL-6R subunit beta,IL-6R-beta,IL-6RB,Membrane glycoprotein 130,Oncostatin-M receptor subunit alpha
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
IL6ST
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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