935106861
info@markelab.com
Precio
525€ (96 tests)
Mouse High Mobility Group Protein B1 (HMGB1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse HMGB1 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.
HMGB1 is a non-histone nuclear protein involved in DNA repair, replication, and transcriptional regulation, but it also functions as a damage-associated molecular pattern (DAMP) protein when released extracellularly Upon cellular stress or necrosis, HMGB1 is actively secreted or passively released, triggering immune responses by interacting with receptors such as RAGE and TLR4 HMGB1 is critical in mediating inflammation, immune activation, and tissue injury, playing roles in diseases like sepsis, autoimmune disorders, and cancer It promotes cell migration, angiogenesis, and tumor progression, while dysregulated HMGB1 signaling is linked to chronic inflammation and metastasis Targeting HMGB1 holds therapeutic promise for modulating immune responses in inflammatory diseases, neurodegeneration, and cancer
ELISA Kits
High Mobility Group Protein B1 (HMGB1)
Mouse
15.6 pg/ml - 1000 pg/ml
9.38 pg/ml
Sandwich
Quantitative
Colorimetric
Serum,Plasma,Tissue homogenates,Cell lysates,Other biological fluids
96 tests
HMG1,HMG3,HMG-1,SBP-1,Amphoterin
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
HMGB1
No
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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