Mouse Hepatocyte Growth Factor (HGF) Protein

Este producto es parte de HGF - Hepatocyte Growth Factor
Product Graph
247€ (10 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Hepatocyte Growth Factor (HGF) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx067069
tested applications
WB, SDS-PAGE

Description

Recombinant Hepatocyte Growth Factor (HGF) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Hepatocyte Growth Factor (HGF)
Host
E. coli
Origin
Mouse
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 26.5 kDa  Observed MW (SDS-PAGE): 27 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Asp482-Val710
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q08048
Alias
SF,HGFB,HPTA,F-TCF,DFNB39,Fibroblast-Derived Tumor Cytotoxic Factor
Background
Protein HGF
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Hepatocyte Growth Factor (HGF), also known as scatter factor, is a multifunctional cytokine primarily secreted by mesenchymal cells. It plays a pivotal role in various physiological and pathological processes, including cell proliferation, migration, morphogenesis, and angiogenesis. HGF exerts its biological effects through binding to its receptor, c-MET, a tyrosine kinase receptor highly expressed on epithelial cells, endothelial cells, and other cell types. This ligand-receptor interaction activates numerous signaling pathways, such as PI3K/AKT and MAPK, promoting tissue regeneration and wound healing. HGF is critically involved in liver regeneration and repair mechanisms, hence its name, but it also has significant implications in tumor progression and metastasis in cancers where c-MET is overexpressed or dysregulated. Clinically, HGF and its receptor c-MET are being explored as therapeutic targets for cancer treatments, given their role in oncogenesis and tumor angiogenesis. Elevated HGF levels in plasma have also been investigated as potential biomarkers for various diseases, including liver dysfunction and cancers.

Related Products

EH0159

Human HGF (Hepatocyte Growth Factor) ELISA Kit

Ver Producto
EP0215

Porcine HGF (Hepatocyte Growth Factor) ELISA Kit

Ver Producto
ER0027

Rat HGF (Hepatocyte Growth Factor) ELISA Kit

Ver Producto