Mouse Heparan Sulfate Proteoglycan 2 (HSPG2) Protein
208€ (10 µg)
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935106861
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name
Mouse Heparan Sulfate Proteoglycan 2 (HSPG2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx653717
tested applications
WB, SDS-PAGE
Description
Mouse Heparan Sulfate Proteoglycan 2 (HSPG2) Protein is a Recombinant Mouse protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Heparan Sulfate Proteoglycan 2 (HSPG2) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.3 kDa Observed MW: 40 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Glu4012-Glu4304 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q05793 |
| Gene ID | 15530 |
| Alias | PLC,SJA,SJS,HSPG,SJS1, PRCAN,HSPG,Perlecan,Basement membrane-specific heparan sulfate proteoglycan core protein,Schwartz-Jampel syndrome 1,chondrodystrophic myotonia |
| Background | Protein HSPG2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Heparan sulfate proteoglycan 2 (HSPG2), also known as perlecan, is a significant component of the extracellular matrix (ECM) in many tissues, including basement membranes. HSPG2 plays a crucial role in various physiological processes such as cell adhesion, proliferation, differentiation, and migration. It is synthesized as a large multidomain protein and is extensively glycosylated. Perlecan is ubiquitous in the body, present in vascular endothelial cells, the central nervous system, skeletal muscle, and other tissues. Its importance is underscored by its involvement in numerous developmental and pathological conditions, including cancer, cardiovascular diseases, and genetic disorders like Schwartz-Jampel syndrome and Dyssegmental Dysplasia Silverman-Handmaker type.
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