HSPG2-Specific antibody
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935106861
info@markelab.com
name
HSPG2-Specific antibody
category
Primary Antibodies
provider
FineTest
reference
FNab04063
tested applications
ELISA, WB
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | heparan sulfate proteoglycan 2 (HSPG2) |
| Host | Rabbit |
| Reactivity | Human, Mouse, Rat |
| Recommended Dilution | WB: 1:200-1:1000 |
| Clonality | polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Observed MW | 469 kDa |
| Purity | ≥95% as determined by SDS-PAGE |
| Purification | Immunogen affinity purified |
| Size 1 | 100µg |
| Form | liquid |
| Tested Applications | ELISA, WB |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.) |
| UniProt ID | P98160 |
| Alias | PLC,SJA,SJS,HSPG,SJS1, PRCAN,HSPG,Perlecan,Basement membrane-specific heparan sulfate proteoglycan core protein,Schwartz-Jampel syndrome 1,chondrodystrophic myotonia |
| Background | Antibody anti-HSPG2 |
| Status | RUO |
| Note | Mol. Weight 469 kDa |
Heparan sulfate proteoglycan 2 (HSPG2), also known as perlecan, is a significant component of the extracellular matrix (ECM) in many tissues, including basement membranes. HSPG2 plays a crucial role in various physiological processes such as cell adhesion, proliferation, differentiation, and migration. It is synthesized as a large multidomain protein and is extensively glycosylated. Perlecan is ubiquitous in the body, present in vascular endothelial cells, the central nervous system, skeletal muscle, and other tissues. Its importance is underscored by its involvement in numerous developmental and pathological conditions, including cancer, cardiovascular diseases, and genetic disorders like Schwartz-Jampel syndrome and Dyssegmental Dysplasia Silverman-Handmaker type.
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