Mouse Glycoprotein 5 (GP5) ELISA Kit
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935106861
info@markelab.com
Precio
611€ (96 tests)
Elisa kits for GP5
proveedor
Abbexareference
abx352777Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Glycoprotein 5 (GP5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Glycoprotein 5 (GP5) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Glycoprotein V (GP5) is a key platelet membrane protein that functions as a part of the GPIb-IX-V complex, a receptor system primarily responsible for mediating platelet adhesion during vascular injury. This complex is crucial for the initial steps of platelet plug formation, which is essential in the process of hemostasis, particularly in the high-shear conditions of arterial blood flow. GP5 serves as an accessory component in the complex, complementing the roles of other glycoproteins like GPIbα (GP1BA), GPIbβ (GP1BB), and GPIX (GP9). The GPIb-IX-V complex, including GP5, binds to von Willebrand factor (vWF), which facilitates platelet tethering to the damaged endothelium under conditions of high shear stress. Although GP5 is not the primary binding site for vWF (that role belongs to GP1BA), it contributes to the structural integrity and function of the receptor. GP5 may also interact with other ligands and is thought to regulate the binding activity of the GPIb-IX-V complex.
Características del producto
category
ELISA Kits
immunogen target
Glycoprotein 5 (GP5)
reactivity
Mouse
test range
0.625 ng/ml - 40 ng/ml
sensitivity
0.38 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
GPV,CD42d,Platelet glycoprotein V,GPV,Glycoprotein 5,CD42d
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
GP5
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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