Mouse Glycophorin A (GYPA) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for GYPA
proveedor
Abbexareference
abx255160Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Glycophorin A (GYPA) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Glycophorin A (GYPA) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
Glycophorin A (GYPA) is a major sialoglycoprotein found on the membrane of human red blood cells (RBCs) and plays a crucial role in the structure and function of the erythrocyte membrane. As a prominent surface protein, it is highly glycosylated and carries sialic acid residues, which contribute to the overall negative charge on the RBC surface, helping to prevent cell aggregation and maintain blood flow. GYPA is most recognized for its involvement in the MNS blood group system, which includes the MN and Ss antigens; variations in the GYPA gene form the molecular basis for these antigenic determinants. This protein is highly relevant in transfusion medicine due to its immunogenic potential and role in blood group antigenicity. In addition to its structural role, GYPA interacts with various pathogens, particularly Plasmodium falciparum, the causative agent of malaria. This interaction is significant for the pathogen’s adhesion to RBCs during infection. GYPA also functions as a receptor for viruses like influenza, playing a broader role in infectious disease dynamics.
Características del producto
category
ELISA Kits
immunogen target
Glycophorin A (GYPA)
reactivity
Mouse
test range
0.625 ng/ml - 40 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
MNS blood group,MN,GPA,MNS,GPSAT,PAS-2,CD235a,MN sialoglycoprotein,Sialoglycoprotein alpha
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
GYPA
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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