Mouse Frizzled Homolog 10 (FZD10) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Frizzled Homolog 10 (FZD10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx524539
tested applications
ELISA
Description
Mouse Frizzled-10 (FZD10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Frizzled-10 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Frizzled Homolog 10 (FZD10) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.07 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8BKG4 |
| Gene ID | 93897 |
| Alias | FZD10,Frizzled Homolog 10,Fz10,FzE7,CD350,FZ-10,hFz10,Frizzled class receptor 10 |
| Background | Elisa kits for FZD10 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
FZD10 is a Wnt receptor predominantly mediating canonical Wnt/β-catenin signaling, playing crucial roles in embryogenesis, tissue regeneration, and tumor progression. It is highly expressed in the nervous system, skeletal tissues, and certain cancers. During development, FZD10 regulates processes like cell proliferation, differentiation, and tissue patterning, particularly in neural and skeletal systems. In cancer, FZD10 is overexpressed in tumors such as synovial sarcoma, colorectal cancer, and hepatocellular carcinoma, where it drives Wnt/β-catenin signaling to promote cell survival, proliferation, and metastasis. Its expression correlates with poor prognosis, therapy resistance, and enhanced tumor progression. FZD10 also plays roles in tissue repair and regeneration by regulating stem cell behavior and promoting cell renewal. Targeting FZD10 with monoclonal antibodies and small-molecule inhibitors is being explored as a therapeutic approach for Wnt-driven cancers, particularly synovial sarcoma. Dysregulation of FZD10 contributes to developmental defects, cancer metastasis, and tissue-specific diseases, highlighting its importance in both normal development and disease pathology.
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