Mouse Free Fatty Acid Receptor 1 (FFAR1) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Free Fatty Acid Receptor 1 (FFAR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx555651
tested applications
ELISA
Description
Mouse Free Fatty Acid Receptor 1 (FFAR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Free fatty acid receptor 1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Free Fatty Acid Receptor 1 (FFAR1) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q76JU9 |
| Alias | FFAR1,GPR40,FFA1R,G protein-coupled receptor 40 |
| Background | Elisa kits for FFAR1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
FFAR1, also known as GPR40, is a G protein-coupled receptor primarily expressed in pancreatic β-cells, where it mediates the effects of medium- and long-chain free fatty acids (FFAs). FFAR1 activation enhances glucose-stimulated insulin secretion through Gq-mediated signaling pathways, including activation of phospholipase C (PLC), increased intracellular calcium, and protein kinase C (PKC) signaling. It plays a critical role in metabolic regulation by linking dietary fat intake to insulin release, thereby maintaining glucose homeostasis. FFAR1 is a promising therapeutic target for type 2 diabetes, where selective agonists are being explored to enhance insulin secretion without causing hypoglycemia. In addition to its metabolic role, FFAR1 is expressed in the brain and has been linked to neuroprotective functions. Dysregulation of FFAR1 signaling contributes to insulin resistance, obesity, and inflammation. Its dual role in metabolic regulation and neurological health positions FFAR1 as a key target for diabetes treatment and potential neurodegenerative therapies.
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