Mouse DENN domain-containing protein 1C (DENND1C) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse DENN domain-containing protein 1C (DENND1C) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx510093
tested applications
ELISA
Description
Mouse DENN domain-containing protein 1C (DENND1C) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse DENN domain-containing protein 1C concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DENN domain-containing protein 1C (DENND1C) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8CFK6 |
| Gene ID | 70785 |
| Alias | FAM31C,Connecdenn 3 ,Protein FAM31C |
| Background | Elisa kits for DENND1C |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DENN domain containing 1C (DENND1C) functions as a guanine nucleotide exchange factor (GEF) for Rab GTPases, primarily Rab35, and is essential for regulating endosomal recycling, membrane dynamics, and vesicular trafficking processes. Through its DENN domain, DENND1C facilitates the activation of Rab35 by catalyzing the exchange of GDP for GTP, ensuring proper vesicle sorting and transport within the cell. It plays a key role in cytokinesis by contributing to the recycling of plasma membrane components required for cell division. DENND1C is also involved in receptor recycling, signal transduction, and membrane trafficking, which are critical for maintaining cellular homeostasis. Its expression across a variety of tissues indicates its broad functionality, but recent research highlights its specific roles in immune responses, including antigen presentation and cytokine signaling. Dysregulation of DENND1C has been associated with defects in membrane trafficking and signaling, suggesting potential links to immune disorders and cellular stress responses.
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