Mouse Dedicator of cytokinesis protein 3 (DOCK3) ELISA Kit

Este producto es parte de DOCK - Dedicator of Cytokinesis
Mouse Dedicator of cytokinesis protein 3 (DOCK3) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOCK3

proveedor

Abbexa

reference

abx510792

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Dedicator of cytokinesis protein 3 (DOCK3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 3 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DOCK3, or MOCA, is a neuron-specific GEF for Rac1 that regulates neurite outgrowth, axonal growth, and synaptic plasticity in the CNS. It mediates actin rearrangement, promoting axonal guidance and dendritic remodeling. Highly expressed in neurons, DOCK3 maintains synapse connectivity and supports neuroprotection. Dysregulation contributes to neurodegenerative diseases like Alzheimer’s, where it influences tau phosphorylation and cell survival pathways such as ERK/Akt activation. DOCK3 deficiency causes motor and cognitive impairments in mouse models, highlighting its role in neuronal development, CNS recovery, and axonal regeneration.

Características del producto

category

ELISA Kits


immunogen target

Dedicator of cytokinesis protein 3 (DOCK3)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

DOCK3, MOCA, PBP, Dock3, dedicator of cytokinesis 3, NEDIDHA


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOCK3


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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