Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit
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Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DOCK10
proveedor
Abbexareference
abx510777Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 10 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
DOCK10 is a GEF for Rac1 and Cdc42, involved in regulating actin cytoskeletal dynamics, cell migration, and lymphocyte polarization. It is highly expressed in hematopoietic cells and epithelial tissues, promoting B-cell activation, dendritic cell migration, and immune surveillance. DOCK10 mediates filopodia and lamellipodia formation, enhancing membrane protrusion during cell migration. It is implicated in immune responses, particularly in B and T cells, where it supports polarization and chemotaxis. Dysregulation is associated with immune dysfunction and cancer metastasis through enhanced cell motility. Knockout models show defects in lymphocyte migration and immune cell activation.
Características del producto
category
ELISA Kits
immunogen target
Dedicator of cytokinesis protein 10 (DOCK10)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
DOCK10, KIAA0694, ZIZ3,Zizimin-3,DRIP2, Nbla10300
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DOCK10
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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