Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx510777
tested applications
ELISA
Description
Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 10 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Dedicator of cytokinesis protein 10 (DOCK10) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8BZN6 |
| Gene ID | 210293 |
| Alias | DOCK10, KIAA0694, ZIZ3,Zizimin-3,DRIP2, Nbla10300 |
| Background | Elisa kits for DOCK10 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DOCK10 is a GEF for Rac1 and Cdc42, involved in regulating actin cytoskeletal dynamics, cell migration, and lymphocyte polarization. It is highly expressed in hematopoietic cells and epithelial tissues, promoting B-cell activation, dendritic cell migration, and immune surveillance. DOCK10 mediates filopodia and lamellipodia formation, enhancing membrane protrusion during cell migration. It is implicated in immune responses, particularly in B and T cells, where it supports polarization and chemotaxis. Dysregulation is associated with immune dysfunction and cancer metastasis through enhanced cell motility. Knockout models show defects in lymphocyte migration and immune cell activation.
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Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody
Dedicator of Cytokinesis Protein 10 (DOCK10) Antibody is a Rabbit Polyclonal antibody for the detection of Dedicator of Cytokinesis Protein 10 (DOCK10).
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