Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit

Este producto es parte de DOCK - Dedicator of Cytokinesis
Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DOCK10

proveedor

Abbexa

reference

abx510777

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse Dedicator of cytokinesis protein 10 (DOCK10) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Dedicator of cytokinesis protein 10 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DOCK10 is a GEF for Rac1 and Cdc42, involved in regulating actin cytoskeletal dynamics, cell migration, and lymphocyte polarization. It is highly expressed in hematopoietic cells and epithelial tissues, promoting B-cell activation, dendritic cell migration, and immune surveillance. DOCK10 mediates filopodia and lamellipodia formation, enhancing membrane protrusion during cell migration. It is implicated in immune responses, particularly in B and T cells, where it supports polarization and chemotaxis. Dysregulation is associated with immune dysfunction and cancer metastasis through enhanced cell motility. Knockout models show defects in lymphocyte migration and immune cell activation.

Características del producto

category

ELISA Kits


immunogen target

Dedicator of cytokinesis protein 10 (DOCK10)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

DOCK10, KIAA0694, ZIZ3,Zizimin-3,DRIP2, Nbla10300


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DOCK10


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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