Mouse DDB1- and CUL4-associated factor 7 (DCAF7) ELISA Kit

Este producto es parte de DCAF - DDB1 and CUL4 associated factor
Mouse DDB1- and CUL4-associated factor 7 (DCAF7) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DCAF7

proveedor

Abbexa

reference

abx509778

Tested Applications

ELISA

reactivity

Mouse

status

RUO

clonality

Descripción

Mouse DDB1- and CUL4-associated factor 7 (DCAF7) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse DDB1- and CUL4-associated factor 7 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

DDB1 and CUL4 associated factor 7 (DCAF7), also known as WDR68, functions as a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex and plays a critical role in protein ubiquitination and degradation. DCAF7 contains WD40 repeats, which facilitate specific protein-protein interactions, allowing the recognition and recruitment of substrates to the E3 ligase complex. It is particularly notable for its involvement in developmental signaling pathways, such as the JNK and Wnt pathways, where it regulates the stability of key transcription factors and signaling molecules. DCAF7 has also been implicated in craniofacial development and neural crest cell differentiation, with studies showing its interactions with kinases such as DYRK1A, which is crucial for neuronal development. Its dysregulation has been associated with developmental abnormalities, underscoring its importance in cellular signaling and tissue formation. Further research is needed to fully elucidate its substrate spectrum and broader biological roles.

Características del producto

category

ELISA Kits


immunogen target

DDB1- and CUL4-associated factor 7 (DCAF7)


reactivity

Mouse


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

AN11,HAN11,WDR68,SWAN-1,WD repeat-containing protein An11 homolog,WD repeat-containing protein 68


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DCAF7


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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