Mouse Cytosolic Carboxypeptidase 2 (AGBL2) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse Cytosolic Carboxypeptidase 2 (AGBL2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx504997
tested applications
ELISA
Description
Mouse Cytosolic Carboxypeptidase 2 (AGBL2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse AGBL2/CCP2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cytosolic Carboxypeptidase 2 (AGBL2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8CDK2 |
| Alias | CCP2 |
| Background | Elisa kits for AGBL2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AGBL2 is another tubulin-modifying enzyme that regulates microtubule stability by cleaving polyglutamate chains from tubulin. It is expressed in various tissues, including the brain, where it contributes to neuronal function, axonal transport, and synaptic organization. AGBL2 plays a role in neurodegenerative diseases, with studies linking its dysregulation to tauopathies, including Alzheimer's disease, where abnormal polyglutamylation of microtubules contributes to neuronal dysfunction. In addition to its neural roles, AGBL2 has been implicated in cancer, where it modulates cell division and migration through its influence on the cytoskeleton.
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