Mouse Cyclic ADP Ribose Hydrolase (CD38) Protein

Este producto es parte de CD38 - CD38 molecule
Mouse Cyclic ADP Ribose Hydrolase (CD38) Protein

Pida mas información

935106861

info@markelab.com

Precio

234€ (10 µg)

Protein CD38

proveedor

Abbexa

reference

abx066192

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Mouse Cyclic ADP Ribose Hydrolase (CD38) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).


Background

CD38 is a multifunctional membrane glycoprotein expressed on a variety of cells, including immune cells (B cells, T cells, monocytes, and natural killer cells), as well as non-hematopoietic cells like those in the pancreas, brain, and muscle. Initially identified as a cell-surface receptor on lymphocytes, CD38 has since been recognized for its roles in enzyme-mediated metabolism, cell adhesion, and signal transduction. This protein is particularly well-known for its enzymatic activity in catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which serves as an important second messenger in calcium signaling pathways. CD38 plays crucial roles in the regulation of intracellular calcium levels, influencing processes such as cell activation, proliferation, and differentiation.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Cyclic ADP Ribose Hydrolase (CD38)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 32.2 kDa Observed MW (SDS-PAGE): 29 kDa Concentration: Prior to lyophilization: 120 µg/ml Sequence Fragment: Thr54-Arg301 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD38


dry ice

No


availability

Shipped within 5-7 working days.


alias

ADPRC1,Cadpr1,ADPRC 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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