Mouse Cyclic ADP Ribose Hydrolase (CD38) Protein
234€ (10 µg)
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name
Mouse Cyclic ADP Ribose Hydrolase (CD38) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx066192
tested applications
WB, SDS-PAGE
Description
Mouse Cyclic ADP Ribose Hydrolase (CD38) is a recombinant Mouse protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Cyclic ADP Ribose Hydrolase (CD38) |
| Host | E. coli |
| Origin | Mouse |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 32.2 kDa Observed MW (SDS-PAGE): 29 kDa Concentration: Prior to lyophilization: 120 µg/ml Sequence Fragment: Thr54-Arg301 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 10 mM PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in 10 mM PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P56528 |
| Alias | ADPRC1,Cadpr1,ADPRC 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1 |
| Background | Protein CD38 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD38 is a multifunctional membrane glycoprotein expressed on a variety of cells, including immune cells (B cells, T cells, monocytes, and natural killer cells), as well as non-hematopoietic cells like those in the pancreas, brain, and muscle. Initially identified as a cell-surface receptor on lymphocytes, CD38 has since been recognized for its roles in enzyme-mediated metabolism, cell adhesion, and signal transduction. This protein is particularly well-known for its enzymatic activity in catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which serves as an important second messenger in calcium signaling pathways. CD38 plays crucial roles in the regulation of intracellular calcium levels, influencing processes such as cell activation, proliferation, and differentiation.
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