Cyclic ADP Ribose Hydrolase (CD38) Antibody
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935106861
info@markelab.com
Precio
312€ (60 µl)
Antibody anti-CD38
proveedor
Abbexareference
abx001411Tested Applications
WB, IHCreactivity
Human, Mouse, Ratstatus
RUOclonality
PolyclonalDescripción
CD38 Antibody is a Rabbit Polyclonal antibody against CD38. CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling.
Background
CD38 is a multifunctional membrane glycoprotein expressed on a variety of cells, including immune cells (B cells, T cells, monocytes, and natural killer cells), as well as non-hematopoietic cells like those in the pancreas, brain, and muscle. Initially identified as a cell-surface receptor on lymphocytes, CD38 has since been recognized for its roles in enzyme-mediated metabolism, cell adhesion, and signal transduction. This protein is particularly well-known for its enzymatic activity in catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which serves as an important second messenger in calcium signaling pathways. CD38 plays crucial roles in the regulation of intracellular calcium levels, influencing processes such as cell activation, proliferation, and differentiation.
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Human, Mouse, Rat
immunogen target
Cyclic ADP Ribose Hydrolase (CD38)
host
Rabbit
isotype
IgG
conjugation
Unconjugated
form
Liquid
tested applications
WB, IHC
purification
Purified by affinity chromatography.
recommended dilution
WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
buffer
PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
size 1
60 µl
size 2
120 µl
size 3
200 µl
storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
or code
CD38
dry ice
No
availability
Shipped within 5-10 working days.
alias
ADPRC1,Cadpr1,ADPRC 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1
uniprot id
NCBI accession
NP_001766.2
note
Concentration: 1 mg/ml -
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