Mouse CUB Domain Containing Protein 1 (CDCP1) Protein

Este producto es parte de CDCP1 - CUB domain containing protein 1
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1079€ (50 µg)

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935106861
info@markelab.com
name
Mouse CUB Domain Containing Protein 1 (CDCP1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692432
tested applications
SDS-PAGE

Description

Mouse CDCP1 Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse CDCP1 (Q5U462) (Met1-Leu666) was expressed with a C-terminal polyhistidine tag.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
CDCP1
Host
HEK293 cells
Origin
Mouse
Observed MW
Molecular Weight: 73.3 kDa
Sequence Fragment: Met1-Leu666
Tag: C-terminal His tag
Validity: The validity for this protein is 12 months.
Expression
Recombinant
Purity
> 96% (SDS-PAGE)
Size 1
50 µg
Form
 
Tested Applications
SDS-PAGE
Buffer
Lyophilized from sterile PBS, pH 7.4.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q5U462
Alias
Membrane glycoprotein gp140,CD318,TRASK,SIMA135,Subtractive immunization M plus HEp3-associated 135 kDa protein
Background
Protein CDCP1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CDCP1 (CUB Domain Containing Protein 1), also known as CD318 or Trask, is a transmembrane protein widely expressed across cell types, including epithelial cells, stem cells, and notably in certain types of cancer cells. CDCP1 is known for its involvement in various cellular processes, including cell adhesion, migration, and signal transduction. It is a single-pass membrane protein characterized by extracellular CUB domains, which are implicated in protein-protein interactions, especially in cell communication and adhesion mechanisms. CDCP1 plays a crucial role in cancer biology, as its overexpression or aberrant activation has been observed in multiple malignancies, such as lung, colon, and breast cancer, where it contributes to processes like invasion, metastasis, and resistance to apoptosis. This makes CDCP1 an important molecule in cancer progression and a potential target for therapeutic interventions. Moreover, CDCP1 is implicated in non-cancerous biological pathways, including wound healing and tissue remodeling, which involve dynamic changes in cell adhesion and migration.

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