Mouse Complement Receptor 2 / CD21 (CR2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CR2
proveedor
Abbexareference
abx513902Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse Complement Receptor 2 / CD21 (CR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Complement Receptor 2 / CD21 (CR2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CR2, also known as complement receptor type 2 (CR2) or CD21, is a crucial protein involved in the immune response, particularly in the regulation and activation of B cells and the complement system. It serves as a receptor for fragments of complement component C3, specifically C3d, C3dg, and iC3b, which are breakdown products of C3b, an integral part of the complement system. By binding these complement fragments, CR2 plays a key role in amplifying the immune response and facilitating interactions between the innate and adaptive arms of the immune system. CR2 is predominantly expressed on the surface of B lymphocytes, follicular dendritic cells, and some epithelial cells. Its most well-known function is to enhance B-cell activation by linking the complement system to the B-cell receptor (BCR) signaling pathway. This enhances B-cell sensitivity to antigens, especially during the formation of immunological memory.
Características del producto
category
ELISA Kits
immunogen target
Complement Receptor 2 / CD21 (CR2)
reactivity
Mouse
test range
0.78 ng/ml - 50 ng/ml
sensitivity
< 0.392 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CR,C3DR,CD21,CVID7,SLEB9,Complement receptor type 2,Complement C3d receptor,Epstein-Barr virus receptor,EBV receptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CR2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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