Mouse CMRF35-Like Molecule 8 (CD300A) Protein
507€ (50 µg)
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935106861
info@markelab.com
name
Mouse CMRF35-Like Molecule 8 (CD300A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx691243
tested applications
SDS-PAGE
Description
Mouse CD300A Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the mouse CD300A (Q6SJQ0-1) (Met 1-Arg 183) extracellular domain was fused with the Fc region of human IgG1 at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CD300A |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 44.2 kDa Sequence Fragment: Met1-Arg183 Tag: C-terminal Fc tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 92% (SDS-PAGE) |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q6SJQ0-1 |
| Alias | CMRF35H,IGSF12,CMRF-35-H9,CMRF35-H9,IRC1/IRC2,Immunoglobulin superfamily member 12 |
| Background | Protein CD300A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD300A, also known as immune receptor expressed by myeloid cells (IREM-1) or leukocyte mono-immunoglobulin-like receptor 8 (LMIR8), is a member of the CD300 family of immunoreceptors. This molecule plays a significant role in the regulation of immune responses. It is encoded by the CD300A gene located on the human chromosome 17. CD300A is primarily expressed on the surface of myeloid cells, including monocytes, macrophages, dendritic cells, and some subsets of lymphocytes. The CD300 family consists of several members, each contributing to the regulation of immune cell functions. CD300A, in particular, is recognized for its inhibitory functions, helping to maintain immune homeostasis and preventing overactivation that could lead to autoimmunity.
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