Mouse Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) CLIA Kit

Este producto es parte de CD40LG - CD40 ligand
Mouse Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) CLIA Kit
845€ (96 tests)

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Name
Mouse Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG) CLIA Kit
Category
CLIA Kits
Provider
Abbexa
Reference
abx196336
Tested Applications
CLIA

Description

Mouse Cluster Of Differentiation 40 Ligand (CD40L) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
CLIA Kits
Immunogen Target
Cluster of Differentiation 40 Ligand / TNFSF5 (CD40LG)
Reactivity
Mouse
Detection Method
Chemiluminescent
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
15.62 pg/ml - 1000 pg/ml
Sensitivity
< 6.7 pg/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard: Lyophilized
Tested Applications
CLIA
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-20 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
Alias
T-cell antigen Gp39,IGM,IMD3,TRAP,gp39,CD154,CD40L,HIGM1,T-BAM,TNFSF5,hCD40L,TNF-related activation protein,Tumor necrosis factor ligand superfamily member 5
Background
CLIA Kits CD40LG
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES.  The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.  Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

CD40 ligand (CD40LG), also known as CD154 or TNFSF5, is a transmembrane protein expressed primarily on the surface of activated T cells and, to a lesser extent, on platelets and other cell types. It is a key member of the tumor necrosis factor (TNF) superfamily and functions as a ligand for CD40, a receptor found on the surface of various immune cells, including B cells, dendritic cells, macrophages, and endothelial cells. CD40LG-CD40 interactions are essential for effective immune responses, promoting T-cell-B-cell cooperation, antigen presentation, and the production of antibodies. Mutations in CD40LG are linked to X-linked hyper-IgM syndrome (XHIM), a primary immunodeficiency disorder, highlighting the protein's importance in immune system regulation. The CD40LG-CD40 axis also plays a role in the development of autoimmune diseases, cardiovascular disorders, and cancer, where the interaction is implicated in chronic inflammation and pathological immune activation.

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