Mouse Cluster Of Differentiation 320 (CD320) Protein

Este producto es parte de CD320 - CD320 molecule
Mouse Cluster Of Differentiation 320 (CD320) Protein

Pida mas información

935106861

info@markelab.com

Precio

212.5€ (10 µg)

Protein CD320

proveedor

Abbexa

reference

abx655907

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Cluster Of Differentiation 320 Protein is a recombinant Mouse protein expressed in E. coli.


Background

CD320, also known as the CD320 molecule or the transcobalamin receptor, is a cell surface protein involved in the transport and cellular uptake of vitamin B12 (cobalamin). It plays a pivotal role in maintaining cellular cobalamin levels, essential for critical cellular functions such as DNA synthesis, red blood cell formation, and neurological health. CD320 facilitates the binding and endocytosis of transcobalamin (TC)-bound vitamin B12 into cells, thus supporting cellular metabolism and growth. It is expressed in various tissues, with heightened expression in tissues requiring high levels of cobalamin, such as the liver, kidneys, and certain regions of the brain. This protein is particularly important in hematopoiesis and nervous system function due to its role in maintaining adequate levels of cobalamin for the function of enzymes involved in methylation and mitochondrial DNA synthesis. CD320 is also gaining attention in immunology, as it has been identified on B cells and other antigen-presenting cells (APCs), suggesting a broader immunomodulatory role. Mutations or deficiencies in CD320-mediated cobalamin uptake are associated with metabolic and hematological disorders, highlighting its essential function in human health.

Características del producto

category

Proteins and Peptides


origin

Mouse


host

E. coli


immunogen target

Cluster Of Differentiation 320 (CD320)


host

E. coli


conjugation

Unconjugated


form

Lyophilized


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


expression

Recombinant


purity

> 90% (SDS-PAGE)


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD320


dry ice

No


availability

Shipped within 1-2 months.


alias

Transcobalamin receptor ,8D6,8D6A,TCBLR,TCN2R,TCII-R,sCD320,8D6 antigen,8D6 antigen


note

This product is for research use only. <p></p> Not for human consumption, cosmetic, therapeutic or diagnostic use.


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