Mouse Cluster of Differentiation 14 (CD14) Protein

Este producto es parte de CD14 - Cluster of Differentiation 14
Product Graph
234€ (2 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Mouse Cluster of Differentiation 14 (CD14) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680459
tested applications
SDS-PAGE

Description

Mouse Cluster of Differentiation 14 (CD14) Protein is a recombinant protein produced in Sf9, Baculovirus cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Cluster of Differentiation 14 (CD14)
Host
Insect
Origin
Mouse
Conjugation
Unconjugated
Expression
Recombinant
Purity
> 90% (SDS-PAGE)
Size 1
2 µg
Size 2
10 µg
Size 3
1 mg
Form
Liquid 
Tested Applications
SDS-PAGE
Availability
Shipped within 5-10 working days.
Dry Ice
No
Alias
Cluster Of Differentiation 14,CD14,Myeloid Cell-Specific Leucine-Rich Glycoprotein,Monocyte differentiation antigen CD14
Background
Protein CD14
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD14 is a pattern recognition receptor (PRR) expressed on the surface of monocytes, macrophages, and neutrophils, where it plays a key role in the innate immune response CD14 functions as a co-receptor for the detection of lipopolysaccharides (LPS) derived from the outer membrane of Gram-negative bacteria It forms a complex with LPS-binding protein (LBP) and transduces signals via the Toll-like receptor 4 (TLR4)-MD2 complex, initiating downstream activation of nuclear factor kappa B (NF-κB) and subsequent production of pro-inflammatory cytokines CD14 exists in two forms, a membrane-bound form (mCD14) and a soluble form (sCD14), both of which contribute to LPS recognition and systemic inflammatory responses Dysregulation of CD14 signaling has been implicated in sepsis, chronic inflammatory diseases, and autoimmune disorders Elevated levels of soluble CD14 serve as a biomarker for monocyte activation in conditions such as HIV, cardiovascular disease, and metabolic disorders

Related Products

APC-30058

APC Anti-Human CD14(M5E2)

Ver Producto
EB0149

Bovine CD14 (Monocyte differentiation antigen CD14) ELISA Kit

Ver Producto
EM0039

Mouse CD14 (Monocyte differentiation antigen CD14) ELISA Kit

Ver Producto