Mouse Cleavage stimulation factor subunit 2 tau variant (CSTF2T) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Cleavage stimulation factor subunit 2 tau variant (CSTF2T) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx508956
tested applications
ELISA
Description
Mouse Cleavage stimulation factor subunit 2 tau variant (CSTF2T) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Cleavage stimulation factor subunit 2 tau variant concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Cleavage stimulation factor subunit 2 tau variant (CSTF2T) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8C7E9 |
| Gene ID | 83410 |
| Alias | CstF-64T,CF-1 64 kDa subunit tau variant,TauCstF-64,Cleavage stimulation factor 64 kDa subunit tau variant |
| Background | Elisa kits for CSTF2T |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Cleavage stimulation factor subunit 2 tau variant (CSTF2T), also referred to as tauCstF-64, is a paralog of CSTF2 and functions in a tissue-specific manner, particularly in the germline. Unlike the ubiquitously expressed CSTF2, CSTF2T is primarily expressed in testis, particularly in pachytene spermatocytes and round spermatids, and is critical for spermatogenesis. It acts as a substitute for CSTF2 in male germ cells, ensuring the proper 3' end processing and polyadenylation of pre-mRNAs during meiosis. CSTF2T has a gene structure lacking introns, which may contribute to its tight regulation during spermatogenic development. Changes in CSTF2T expression have been linked to male infertility, as its deficiency disrupts germ cell-specific mRNA processing pathways required for proper sperm development. Research suggests that CSTF2T plays a role in maintaining RNA processing efficiency and alternative polyadenylation patterns necessary for male gamete formation and overall reproductive health.
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