Mouse Butyrophilin Subfamily 1 Member A1 (BTN1A1) Protein
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Description
Butyrophilin Subfamily 1 Member A1 (BTN1A1) protein is a recombinant Mouse protein expressed in HEK293 cells.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Butyrophilin Subfamily 1 Member A1 (BTN1A1) |
| Host | HEK293 cells |
| Assay Type | Activity: Not tested Sequence Fragment: Ala27-Trp247 Tag: C-terminal 6 His tag |
| Origin | Mouse |
| Observed MW | Calculated MW: 25.4 kDa Observed MW (SDS-PAGE): 32-35 kDa |
| Expression | Recombinant |
| Purity | > 95% (SDS-PAGE) |
| Purification | 0.2 µm filtered prior to lyophilization. |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 5%-8% Trehalose, Mannitol and 0.01% Tween 80. |
| Availability | Shipped within 5-15 working days. |
| Storage | Storage: Store lyophilized between -20 °C and -80°C. Stability: Stable when stored reconstituted at 2-8°C for up to 1 week. Reconstituted aliquots are stable at -20°C for up to 3 months. Shelf Life: 12 months. |
| Dry Ice | No |
| UniProt ID | Q62556 |
| Gene ID | 12231 |
| Alias | BT,BTN,BTN1 |
| Background | Protein BTN1A1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Reconstitute in sterile H2O to prepare a stock solution of concentration 0.25 mg/ml. Do not vortex. Endotoxin Level: < 1.0 EU per µg (LAL method). |
Descripción
Butyrophilin subfamily 1 member A1 (BTN1A1) is a member of the butyrophilin family, which belongs to the immunoglobulin superfamily. The butyrophilin family consists of proteins that play crucial roles in immune regulation and cellular communication. BTN1A1 is primarily known for its role in milk fat globule secretion in mammary epithelial cells and has also been implicated in various immune functions. This protein is of significant interest due to its involvement in both lactation and immune modulation, making it a focal point for studies related to immunology, lactation biology, and related diseases.
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BTN1A1, also named as Butyrophilin subfamily 1 member A1, is a 526 amino acid protein, which contains 1 B30.2/SPRY domain and belongs to the immunoglobulin superfamily. BTN/MOG family. BTN1A1 localizes in the integral component of plasma membrane. BTN1A1 may function in the secretion of milk-fat droplets and may act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. BTN1A1 Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. The calculated molecular weight of BTN1A1 is a 59 kDa, but the modified BTN1A1 protein is about 65-75 kDa.
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