anti- BTN1A1 antibody

Este producto es parte de BTN1A1 - butyrophilin subfamily 1 member A1
anti- BTN1A1 antibody

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935106861

info@markelab.com

Precio

Precio a consultar

Antibody anti-BTN1A1

proveedor

FineTest

reference

FNab09786

Tested Applications

ELISA, WB

reactivity

human

status

RUO

clonality

polyclonal

Descripción

BTN1A1, also named as Butyrophilin subfamily 1 member A1, is a 526 amino acid protein, which contains 1 B30.2/SPRY domain and belongs to the immunoglobulin superfamily. BTN/MOG family. BTN1A1 localizes in the integral component of plasma membrane. BTN1A1 may function in the secretion of milk-fat droplets and may act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. BTN1A1 Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion. The calculated molecular weight of BTN1A1 is a 59 kDa, but the modified BTN1A1 protein is about 65-75 kDa.


Background

Butyrophilin subfamily 1 member A1 (BTN1A1) is a member of the butyrophilin family, which belongs to the immunoglobulin superfamily. The butyrophilin family consists of proteins that play crucial roles in immune regulation and cellular communication. BTN1A1 is primarily known for its role in milk fat globule secretion in mammary epithelial cells and has also been implicated in various immune functions. This protein is of significant interest due to its involvement in both lactation and immune modulation, making it a focal point for studies related to immunology, lactation biology, and related diseases.

Características del producto

category

Primary Antibodies


clonality

polyclonal


reactivity

human


immunogen target

butyrophilin, subfamily 1, member A1


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

liquid


tested applications

ELISA, WB


observerd MW

73 kDa


purity

≥95% as determined by SDS-PAGE


purification

Immunogen affinity purified


recommended dilution

WB: 1:500-1:5000


size 1

100µg


storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)


or code

BTN1A1


alias

BT,BTN,BTN1


note

This product is for research use only.


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