Mouse Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) ELISA Kit
715€ (96 tests)
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935106861
info@markelab.com
name
Mouse Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx255131
tested applications
ELISA
Description
Mouse Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse Breast cancer anti-estrogen resistance protein 3 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Breast Cancer Anti-Estrogen Resistance Protein 3 (BCAR3) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q9QZK2 |
| Alias | BCAR3, NSP2, SH2D3B, breast cancer anti-estrogen resistance 3, AND-34, NSP family adaptor protein, BCAR3 adaptor protein, NSP family member, MIG7 |
| Background | Elisa kits for BCAR3 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
BCAR3, also known as Breast Cancer Anti-Estrogen Resistance Protein 3, is involved in the development of resistance to anti-estrogen therapies in breast cancer, much like its family members BCAR1 and BCAR2. BCAR3 has been shown to participate in signaling pathways that affect cell survival and migration. This protein is often implicated in the progression of cancer cells from an estrogen-dependent to an estrogen-independent state, allowing them to proliferate and survive despite the presence of estrogen inhibitors. BCAR3’s interaction with other molecular players in cell signaling, such as those controlling cytoskeletal reorganization, further contributes to cancer cell invasion and metastasis. Targeting BCAR3 may offer new therapeutic approaches for overcoming resistance in estrogen receptor-positive breast cancer, providing more effective treatments for patients with advanced disease. Its role in cancer progression and therapy resistance makes BCAR3 an important subject of ongoing research in oncology.
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