Mouse Bone Morphogenetic Protein Receptor 1A (BMPR1A) Protein (Active)
1235€ (200 µg)
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935106861
info@markelab.com
name
Mouse Bone Morphogenetic Protein Receptor 1A (BMPR1A) Protein (Active)
category
Proteins and Peptides
provider
Abbexa
reference
abx691923
tested applications
SDS-PAGE
Description
Mouse BMPR1A Protein is a recombinant protein from Mouse produced in HEK293 Cells. A DNA sequence encoding the extracellular domain (Met 1-Arg 152) of mouse ALK3 (NP_033888.2) precursor was expressed, fused with a polyhistidine tag at the C-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | BMPR1A |
| Host | HEK293 cells |
| Origin | Mouse |
| Observed MW | Molecular Weight: 15.8 kDa Sequence Fragment: Met1-Arg152 Tag: C-terminal His tag Validity: The validity for this protein is 12 months. |
| Expression | Recombinant |
| Purity | > 97% (SDS-PAGE) |
| Size 1 | 200 µg |
| Form | |
| Tested Applications | SDS-PAGE |
| Buffer | Lyophilized from sterile PBS, pH 7.4. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C or -80°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| NCBI Accession | NP_033888.2 |
| Alias | Activin receptor-like kinase 3,ALK3,SKR5,ALK-3,CD292,ACVRLK3,BMPR-1A,Serine/threonine-protein kinase receptor R5 |
| Background | Protein BMPR1A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
Bone morphogenetic protein receptor type 1A (BMPR1A) is a receptor for the bone morphogenetic proteins (BMPs), a subgroup of the transforming growth factor-beta (TGF-β) superfamily. BMPs are growth factors and cytokines that play critical roles in embryonic development, skeletal formation, organogenesis, and tissue homeostasis. BMPR1A, also known as ALK3 (Activin receptor-like kinase 3), specifically mediates BMP signaling by interacting with BMP ligands to activate intracellular pathways, influencing processes such as cell growth, differentiation, apoptosis, and repair. This receptor is essential for bone and cartilage development and has critical roles in several cell types across various tissues, with particularly strong influence in skeletal, cardiac, and gastrointestinal systems.
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