Mouse BAG Family Molecular Chaperone Regulator 4 (BAG4) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for BAG4
proveedor
Abbexareference
abx503483Tested Applications
ELISAreactivity
Mousestatus
RUOclonality
Descripción
Mouse BAG Family Molecular Chaperone Regulator 4 (BAG4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse BAG Family Molecular Chaperone Regulator 4 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
BAG cochaperone 4 (BAG4), also known as Rem, is a cochaperone that interacts with the HSP70 and HSP90 chaperone proteins to regulate protein folding, degradation, and cellular stress responses BAG4 plays a critical role in managing protein stability and protecting cells from misfolded proteins that can accumulate under stress It is involved in apoptosis regulation, where it interacts with pro-survival signaling pathways to influence cell fate during stress conditions BAG4 also has a significant role in immune cell function and inflammation, where it regulates the degradation of inflammatory signaling molecules and supports immune cell survival under stress Dysregulation of BAG4 has been linked to autoimmune diseases and cancers, where it enhances the stability of oncogenic proteins and prevents apoptotic signaling in tumor cells Additionally, BAG4 is involved in tissue repair and regeneration, particularly in the context of muscle and nervous tissue BAG4’s function in cellular homeostasis, immune regulation, and stress response pathways underscores its importance in maintaining normal cellular function and preventing pathological conditions
Características del producto
category
ELISA Kits
immunogen target
BAG Family Molecular Chaperone Regulator 4 (BAG4)
reactivity
Mouse
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
BAG-4,SODD,Bcl-2-associated athanogene 4,Silencer of death domains,BAG family molecular chaperone regulator 4
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
BAG4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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