Mouse BAG family molecular chaperone regulator 2 (BAG2) ELISA Kit
715€ (96 tests)
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935106861
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name
Mouse BAG family molecular chaperone regulator 2 (BAG2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx503479
tested applications
ELISA
Description
Mouse BAG family molecular chaperone regulator 2 (BAG2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Mouse BAG family molecular chaperone regulator 2 concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | BAG family molecular chaperone regulator 2 (BAG2) |
| Reactivity | Mouse |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q91YN9 |
| Gene ID | 213539 |
| Alias | BAG-2,dJ417I1.2,Bcl-2-associated athanogene 2,BAG family molecular chaperone regulator 2 |
| Background | Elisa kits for BAG2 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
BAG cochaperone 2 (BAG2) is a protein that functions as a cochaperone for heat shock proteins (HSPs), particularly HSP70, to regulate protein folding and degradation BAG2 plays a key role in controlling the cellular stress response by modulating protein homeostasis under stress conditions It interacts with misfolded proteins and assists in their proper folding or directs them for proteasomal degradation through the ubiquitin-proteasome pathway BAG2 also has roles in the regulation of apoptosis, where it can influence cell survival by interacting with pro-apoptotic factors BAG2 is implicated in various diseases, including cancer, where its expression can promote tumor progression by stabilizing key oncogenic proteins and inhibiting cell death pathways Additionally, BAG2 has been linked to neurodegenerative diseases such as Parkinson's disease, where its role in protein quality control is crucial for preventing the accumulation of toxic protein aggregates Its ability to modulate protein turnover and cell survival pathways highlights BAG2 as an important player in maintaining cellular integrity and a potential target for therapeutic intervention
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